NUMA
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Create a RAID out of drives belonging to the same NUMA node, if your systems are multiprocessor.
To figure out the NUMA node drive, run:
# cat /sys/block/nvme0n1/device/device/numa_node
or via lspci:
# lspci -vvv
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At creation of NVMe-oF target for xiRAID Classic RAID, you can use network adapter of the same NUMA node as NVMe drives.